Cardiac risks with beta agonists
نویسندگان
چکیده
منابع مشابه
Inhaled beta-2 adrenergic receptor agonists and primary cardiac arrest.
PURPOSE We sought to investigate if short-acting, inhaled beta2-adrenergic receptor agonists were associated with higher risk of primary cardiac arrest in patients with asthma or chronic obstructive pulmonary disease (COPD). SUBJECTS AND METHODS We conducted a population-based study involving 454 patients enrolled in a health maintenance organization, aged 40 to 79 years, who had asthma or CO...
متن کاملInhaled beta agonists.
The beta(2) adrenoreceptor is a large molecule of some 413 amino acids. The duration of stimulation of this receptor depends on where and for how long a beta(2) adrenergic drug attaches itself to the beta(2) adrenoreceptor. beta(2) adrenergic drugs have been used for over 5,000 years, but only recently have we had the advantage of adrenergic drugs specific to the beta(2) adrenoreceptor. The sho...
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Inhaled β₂-adrenoceptor (β₂-AR) agonists are considered essential bronchodilator drugs in the treatment of bronchial asthma, both as symptoms-relievers and, in combination with inhaled corticosteroids, as disease-controllers. In this article, we first review the basic mechanisms by which the β₂-adrenergic system contributes to the control of airway smooth muscle tone. Then, we go on describing ...
متن کاملRisk of non-fatal cardiac failure and ischaemic heart disease with long acting beta 2 agonists.
BACKGROUND The long term safety of beta agonists, particularly in patients with heart disease, has not been fully established. METHODS This study accessed the results of three cohort studies involving: 12,294 patients receiving at least one prescription for nedocromil between November 1986 and September 1988; 15,407 patients prescribed salmeterol between December 1990 and May 1991; and 8098 p...
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The 31st French Pharmacovigilance Meeting took place in March 2010 in Bordeaux. Each year this conference examines adverse events reported to regional pharmacovigilance centres by healthcare professionals, as well as the French pharmacovigilance database. The following articles will examine presentations having important practical implications, which provide useful feedback and encourage furthe...
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ژورنال
عنوان ژورنال: Thorax
سال: 1998
ISSN: 0040-6376
DOI: 10.1136/thx.53.12.1094